Conference Agenda
Dec. 1st, 2017 Morning 7:30-12:10
7:30-8:30 Registration
8:30-8:50 Opening Ceremony
Chairs: Prof. Pei Hu and Prof. Qingshan Zheng
Session 1: Development of System Pharmacology
Chairmen: Prof. Wei Lu, Prof. Xiaodong Liu
|
Time |
Lecture Title |
Speaker |
|
08:50-09:20 |
Mechanistic Basis of Systems Pharmacology |
William J. Jusko, Prof. of SUNY at Buffalo, NY, USA |
|
09:20-09:50 |
Breaking the Glass Ceiling: Examining the Perceived Hurdles to Quantitative Systems Pharmacology Modelling |
Amin Rostami-Hodjegan, Prof. of University of Manchester, UK |
Tea Break：09:50-10:20
Session 2: The Impact of Quantitative Pharmacology on Decision and Strategy of Clinical
Studies
Chairmen: Prof. Yi Fang, Prof. Minji Wei
|
Time |
Lecture Title |
Speaker |
|
10:20-10:50 |
Current status of pharmacometrics on drug clinical development in China: cases and milestones |
Qingshan Zheng, |
|
10:50-11:20 |
The role of clinical pharmacology in precision medicine |
Richard Peck, MD/PhD, Global Head of pRED，Roche |
|
11:20-11:50 |
Role of Clinical Pharmacology & Pharmacometrics in Janssen’s Drug Development
|
Amar Sharma, PhD, Head of Global Clin. Pharm. and PM., Janssen |
|
11:50-12:20 |
Challenges and Opportunities in the Development of Neurodegenerative Treatments: The Role of Clinical Pharmacology and Pharmacometrics.
|
Brian Corrigan, PhD, Head of Global Clin. Pharm. and VP, Pfizer |
Dec. 1st, 2017 Afternoon 13:30-17:30
Session 3: The Application and Future of Mechanism-based Physiological Pharmacokinetic
Models and Disease Progression Model
Chairmen: Prof. Guoping Yang、Dr. Ping Liu
|
Time |
Lecture Title |
Speaker |
|
13:30-14:00 |
Cancer Modeling Platform
|
Jin Yan Jin, Global Head of M&S, Genetech |
|
14:00-14:30 |
The Application of Empirical and Mechanism-based Disease Progression Modeling
|
Liping Zhang, PhD, Senior Director, Pharmacometrics US Group Lead, Janssen |
|
14:30-15:00 |
PBPK: from academic research to routine use in drug development
|
Ping Zhao , Ph.D The Bill&Melinda Gates Foundation |
Tea Break：15:00-15:30
Session 4: Model-based Drug Dvelopment Strategy in Biopharmaceutics
Chairmen: Dr. Jun Shi, Dr. Jiansong Yang
|
Time |
Lecture Title |
Speaker |
|
15:30-16:00 |
Translational Modeling of Target-Mediated Drug Disposition and Dynamics |
Donald E. Mager, Prof. of SUNY at Buffalo, NY, USA |
|
16:00-16:30 |
Application of PBPK models in development of therapeutic antibodies |
Yanguang Cao, Assistant Prof. of UNC at Chapel Hill, NC, USA |
|
16:30-17:00 |
PKPD modeling to guide biologics clinical development plan |
Tom Sun, Senior Director, Janssen. |
Panel Discussion：17:00-17:30（All the speakers）
Tea Break：17:30-18:00
Dec. 1st, 2017 Night 18:00-20:30
Salon: How to efficiently conduct early phase new drug development (Offer dinner)
Chairmen: Dr. Qian Zhao, Dr. Xin Zheng
|
Time |
Lecture Title |
Speaker |
|
18:00-18:20 |
Early Drug Development in China - Mosim's Experience
|
Jiansong Yang, Ph D CEO, Mosim. |
|
18:20-18:40 |
Quality By Design (QbD in Clinical Trial) --- Implementaion of Reinforced Operational Control for Clinical Trial
|
Yin Li, Ph D Spring Medical Chief Commercial Officer |
|
18:40-19:00 |
Exploratory and Quantitative Research Strategy of Biomarker
|
Chao Zhang, Ph D AB Sciex |
Panel Discussion: Opportunity and Challenge: Quantitative Pharmacology in the research and development of novel drugs
Chairmen: Dr. Gailing Li
|
Time |
Speaker |
|
19:10-20:30 |
Panel Discussion: Yaning Wang, Liang Zhao, Jinbo Yang, Qingshan Zheng, Pei Hu, Li Chen, Yingxiang Wang, Qingchun Song
|
Dec. 2nd, 2017 Morning 8:30-12:20
Session 5: The Current Status and Future of Quantitative Pharmacology in Drug Evaluation
from the Perspective of Regulation Authority
Chairmen: Prof. Chenyan Gao, Dr. Feng Guo
|
Time |
Lecture Title |
Speaker |
|
08:30-09:00 |
Balance between empiricism and mechanism |
Yaning Wang, Director, Division of PM, CDER/FDA, USA |
|
09:00-09:30 |
The Current Status and Future of Quantitative Pharmacology in Drug Evaluation in China
|
Jinbo Yang, Director, Division of Statistics and Clinical Pharmacology CDE/CFDA, China |
|
09:30-10:00 |
Application of Quantitative Methods and Modeling to Generic Drug Development |
Liang Zhao, Subject Scientist from US |
Tea Break：10:00-10:30
Session 6: The Application of Quantitative Pharmacology in Personalized Medicine and
Bioequivalence Evaluation
Chairmen: Prof. Zheng Jiao, Prof. Haitang Xie
|
Time |
Lecture Title |
Speaker |
|
10:30-11:00 |
Precision Drug Dosing: The Ultimate Patient Centered Pharmacometrics Application to Improve Health
|
Bob Powell, Pharm D Univ. of North Carolina State |
|
11:00-11:30 |
Determination of antibiotic treatment duration and drug resistance control: a new model-based approach |
Jun Shi, PhD, Roche Innovation Center |
|
11:30-12:00 |
Mutual Use of Clinical data from East Asian Countries in Drug Development and Registration
|
Diane Wang, Ph D Pfizer
|
Panel Discussion：12:00-12:20（All the speakers）
Dec. 2nd, 2017 Afternoon13:30-17:30
Session 7: Invited Lectures by Young Researchers
Chairmen: Dr. Hongyun Wang, Dr. Li Li
|
Time |
Lecture Title |
Speaker |
|
13:30-13:45 |
The Application of Pharmacometrics for Early Phase Clinical Development of New Anti-diabetic Drugs |
Dongyang Liu, Ph D, Peking Union Medical College Hospital |
|
13:45-14:00 |
Novel pharmacotherapeutic quantitative guideline: our practice |
Lujin Li, PhD, |
|
14:00-14:15 |
Predicting the clinical doses of two glucocorticoids in the treatment of pancreatic cancer from preclinical studies by PK/PD modeling
|
Qingyu Yao, Ph D, Peking University |
|
14:15-14:30 |
Application and perspective of population pharmacokinetics in drug review |
Hongchan Han, Scientist Division of Statistics and Clinical Pharmacology, CDE/CFDA, China |
|
14:30-14:45 |
Mechanism-based modeling and simulation of the time-kill curve: the biological resistance vs chemical reaction kinetics |
Xiaofen Liu, Ph D Fudan University Huanshan Hospital |
|
14:45-15:00 |
How to optimize the early clinical trial design for Neuro diseases |
Yucheng Sheng, PhD GSK |
Tea Break: 15:00-15:15
Session 7 Part 2 : Invited Lectures by Young Researchers
Chairmen: Dr. Xiaocong Zuo, Dr. Guangli Ma
|
Time |
Lecture Title |
Speaker |
|
15:15-15:30 |
Exploring the Relationship between CYP2D6 Genotype and Phenotype based on Modeling and Quantitative analysis
|
Rui Chen, Ph D, Peking Union Medical College Hospital |
|
15:30-15:45 |
Establishment of pharmacogenetics-based warfarin dosing algorithms with prospective data of Chinese patients using machine learning techniques
|
Qi Pei, Ph D, Xiangya Third Hospital |
|
15:45-16:00 |
Cloud computing in the modeling and simulation |
Lixuan Qian, Ph D, Fudan University Huanshan Hospita |
|
16:00-16:15 |
Impact beyond Gut: a PBPK model for liposome property-performance translation |
Hua He, Ph D, China Pharmaceutical University |
|
16:15-16:30 |
PK prediction in patients with impaired renal function using PBPK, a case study |
Sheng Feng, Ph D, Roche China |
|
16:30-16:45 |
Modeling Combined Immunosuppressive and Anti-inflammatory Effects of Dexamethasone and Naproxen in Rats Predicts the Steroid-Sparing Potential of Naproxen
|
Xiaonan Li, PhD Mosim Co. Ltd. |
Best Poster Awards：16:45-17:10
Youth Paper Award：17:10-17:35
Closing ceremony：17:35-17:45